If you eat Hostess fruit turnover pies can it clog your arteries?

Sugar clogs up your arteries.

No, the fruit pie doesn't enter the arteries. 

A poor diet can lead to health problems that include this. 

Eat enough of them, yeah they can. But I think they are SO sweet, you just cannot eat that many. 

The Hostess fruit pies were basically fried pies with a golden crust and a combination of real fruit and goop inside.

Any fats can ultimately "clog your arteries".